My sister has very advanced small cell lung cancer. She has just started on the chemo durrg called Topecan. This is being used as a second line of chemo drugs. The first chemo durgs used were cisplatin and etoposide, then carboplatin and etoposide. The cancer has continued to spread, from the lung to the liver then the bones and now she just went through radiation for several brain tumors-she was diagnosed in November. What side effects should be expected? Is there any other options except clinical trials? At Southwestern, I was told that they had said to my brother in law that “the radiation would kill all the brain tumors.” But it has really taken a toll on her strength, balance etc. Thank you for any information.